Gateway Reflex and Mechanotransduction

SummaryThe gateway reflex explains how autoreactive CD4+ T cells cause inflammation in tissues that have blood-barriers, such as the central nervous system and retina.It depends on neural activations in response to specific external stimuli, such as gravity, pain, stress, and light, which lead to the secretion of HOME noradrenaline at specific vess

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Resistance characterization and transcriptomic analysis of imipenem-induced drug resistance in Escherichia coli

Background Bacteria can develop resistance to various antibiotics under selective pressure, leading to multifaceted changes in resistance mechanisms.Transcriptomic sequencing allows for the observation of transcriptional level alterations in cells under antibiotic stress.Understanding the Shoe Inserts bacterial response to such stress is essential

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General Concepts in Adult Congenital Heart Disease

Congenital heart disease in adults (adult congenital heart disease) is a growing massager-standard burden for healthcare systems.While infant mortality due to congenital heart disease in the last four decades decreased by almost 3-fold, adult congenital heart disease prevalence increased by more than 2-fold in United States.Adult congenital heart d

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